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A Novel Mouse Model of Duchenne Muscular Dystrophy with a Duplication of DMD Exon 2
Detailed Technology Description
A novel mouse model for testing exon skipping therapies for DMD disease has been generated at Nationwide Children's Hospital. This mouse model carries a duplicated exon (exon2) in the DMD gene as compared to a point mutation in the most common mdx mouse model. This unique dystrophic mouse can serve as a preclinical testing model to test various therapies that mediate exon skipping.
Countries
Not Available
Application No.
None
Country/Region
USA
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