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Compounds for modulating ferroptosis and treating excitotoxic disorders


Summary

This technology describes a class of chemical compounds that specifically modulate cellular ferroptosis to treat a range of excitotoxic disorders.


Technology Benefits

Ferroptosis offers a distinct pathway for the treatment of diseaseSmall molecule inhibitors are easily tuned through medicinal chemistry and inexpensive to produceDistinct cell death mode may provide insight into biological pathways and cell death regulation


Technology Application

Prevention of cell deathInhibition of non-standard cell death pathwaysSpecific targeting of tumorigenic cancer cellsProtection against neurodegenerative diseasesTreatment of a range of excitotoxic disorders


Detailed Technology Description

None


Country/Region

USA

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