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Selectively Targeting Sphingosine-1-Phosphate Receptors (S1PRs) to Treat Liver Diseases
Detailed Technology Description
The inventors have discovered a new therapeutic target for the treatment of liver diseases, such as liver fibrosis and liver cirrhosis.
Others
HDL activation ofendothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration andsuppresses fibrosis in the liver. Bi-Sen Ding et. al., JCI Insight. 2016 Dec 22; 1(21): e87058.
Country/Region
USA
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