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Adenovirus Hexon-Based Anti-Nicotine Vaccine to Treat Nicotine Addiction

Detailed Technology Description

Thisinvention provides a conjugate comprising an isolated adenovirus hexon protein coupledto nicotine or a nicotine analog, as well as a method for using such aconjugate to induce an anti-nicotine immune response to treat and preventnicotine addiction in a human.

Others

Suppression of nicotine-inducedpathophysiology by an adenovirus hexon-based antinicotine vaccine. Hum Gene Ther, 2013, 24,595-603.
Developmentof a highly efficient second generation nicotine-conjugate vaccine to treatnicotine addiction. Published PCT applicationWO2013154744.

Country/Region

USA

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