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Reagents and Methods for Detecting Sirtuin Enzymatic Activity and Screening Sirtuin Modulators

Detailed Technology Description

Thisinvention provides methods and compositions for preparing a sirtuin complex anddetecting a sirtuin in a sample, as well as methods and compositions for screeningand identifying compounds which inhibit or activate the enzymatic activity of asirtuin.

Others

Mechanism-based affinity capture of sirtuins. Org. Biomol. Chemistry, 2011, 9:987-93.
PublishedUS patent application 20130065248-A1

Country/Region

USA

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