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Methods for Stimulating Hematopoietic Stem Recovery by Inhibiting TGFβ Signaling


Detailed Technology Description

This invention discloses methods for promoting hematopoietic recovery after myelosuppression or other hematologic stresses by administering an inhibitor of TGFβ signaling to expand hematopoietic stem and progenitor cells.


Others

TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy. J Exp Med, 2013, 210, 623-39.


Country/Region

USA

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