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Compositions and Methods for the Expansion of Stem Cells

Detailed Technology Description

This invention provides an engineered degradation-resistant HOXB4 protein, materials and methods to produce it, and methods to use this recombinant protein for the ex vivo expansion of hematopoietic stem cells.

Others

Improvedex vivo expansion of adult hematopoietic stem cells by overcoming CUL4-mediateddegradation of HOXB4. Blood, 2013, 121, 4082-9.
COMPOSITIONS AND METHODSFOR THE EXPANSION OF STEM CELLS. WO/2014/120714.

Country/Region

USA

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