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Blocking Induction of Tetrahydrobiopterin to Block Induction of Nitric Oxide Synthesis
Others
Gross SS, et al (1993) Tetrahydrobiopterin synthesis is induced by LPS in vascular smooth muscle and is rate-limiting for nitric oxide production. Adv Exp Med Biol. 338:295-300. Review.
http://tinyurl.com/22dbx5
Kolinsky MA, Gross SS. (2004) The mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory protein. J Biol Chem. 279(39):40677-82.
http://tinyurl.com/23vfdy
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