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Modulators for Sirt2 in Cancer Therapeutics and Assays for Screening Same

Detailed Technology Description

The invention provides methods, assays and compounds associated with sirtuins, specifically Sirt2 mechanisms, for treatment and prevention of cancer.

Others

Patentissued in the U.S. under 9,359,293,U.S. divisional patent application under2016/0279091,and filed in Europe, China, India.
Jing H.,& al. (2016). A SIRT2-Selective Inhibitor Promotes c-Myc OncoproteinDegradation and Exhibits Broad Anticancer Activity. Cancer Cell 29(3):297-310. DOI: 10.1016/j.ccell.2016.02.007
“Researchprobes key protein's role in cancer cell growth” Cornell Chronicle, January24, 2018
“Enzymeinhibitor looks promising against cancer” Cornell Chronicle, March 21, 2016

Country/Region

USA

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