Nanoscale Optical Voltage Sensors

Real time modulation of plasmonic resonance.Enable creations of a new generation of nanoscale voltage sensorsLarger voltage sensitivity detection and mapping capabilities of neuronal electrophysiological signals and brain function connectivityHigh sensitivity, resolution, and throughputCan be flexibly delivered into living tissue via the vascular system and minimally invasive probesCan be expanded in detecting, imaging, monitoring and manipulating neuronal activity

Nanoscale electro-opticsInformation displaysIn vitro and in vivo voltage sensors for highly sensitive real-time monitoring cellular membrane potentialIn situ monitoring of local electric fieldsMonitoring of voltage propagation in neuronsNeuronal and brain mapping

UCLA researchers have developed nanoscale optical voltage sensor. The hybrid structure of the sensor allows active manipulation of light signals at sub-wavelength scale. NOVS can sensitively and rapidly transduce membrane voltage signals into detectable optical signals for direct recording and monitoring.

State Of Development

The invention has been successfully prototyped and demonstrated.

Related Materials

Yin, Anxiang, et al. "Plasmonic/Nonlinear Optical Material Core/Shell Nanorods as Nanoscale Plasmon Modulators and Optical Voltage Sensors." Angewandte Chemie 128.2 (2016): 593-597.

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Tech ID/UC Case

25902/2016-298-0

Related Cases

2016-298-0

USA