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Human Retinal Stem Cell Production

Technology Application

Possible commercial applications may include a use of the method to develop suitable cell types for cell-based therapy to treat retinal degeneration, disease in a dish modeling and drug screening.

Detailed Technology Description

UC San Diego investigators, Drs Kang Zhang, Jiagang Zhao and Adah Almutairi, have developed a rapid and efficient method to produce human multi-potent retinal cells under defined conditions. Remarkably, these cells can be directed toward a specific retinal cell fate in vitro, including RGCs, photoreceptors or RPE. Furthermore, multi-potent retinal cell transplants can survive and integrate and importantly differentiate into photoreceptors in the degenerating retina of RCS rats. This invention may provide a renewable source of cells for therapeutic applications in retinal regeneration.This invention may provide an efficient, cost effective, GMP applicable method for producing both neuronal and non-neuronal retinal cells.

Application No.

20160243285

Others

Tech ID/UC Case

23953/2014-061-0

Related Cases

2014-061-0

Country/Region

USA

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