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Compound for the Prevention Of Rosacea Inflammation

Technology Application

A topical application has the potential to be developed from this invention for rosacea patients.

Detailed Technology Description

Previously an increase in the number of mast cells has been associated with rosacea in patients. Building on this knowledge, UC San Diego researchers have found that a compound that is traditionally used to treat allergic disorders has the ability to block the activation of mast cells and in turn prevent the induction of skin rosacea.

Application No.

9801848

Others

State Of Development

UCSD researchers have not only validated the efficacy of this compound in a murine model, but also have delineated its mechanism of action.

Intellectual Property Info

This technology is available for licensing.

Related Materials

Mast cells are key mediators of cathelicidin-initiated skin inflammation in rosacea. Muto Y, Wang Z, Vanderberghe M, Two A, Gallo RL, Di Nardo A. J Invest Dermatol. 2014 Nov;134(11):2728-36. doi: 10.1038/jid.2014.222. Epub 2014 May 20. PMID: 24844861

Tech ID/UC Case

23458/2013-153-0

Related Cases

2013-153-0

Country/Region

USA

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