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Simple and Rapid Method for the Quantification of Haloginated Dissaccharides (i.e. Sucralose) in an Aqueous Media


Technology Benefits

Fewer steps in comparison to traditional method, high throughput analysisLow volumeInexpensive


Technology Application

Rapid measurement of sucralose in solutionSolutions can be buffers, foods and beverages, as well as biological specimens including urine


Detailed Technology Description

Researchers at UC Santa Cruz have developed a chemical-fluorescent methodology to expedite quantification of sucralose in aqueous and biological solutions. This circumvents the HPLC-MS analytical challenge, which is labor intensive. The invention involves a quenched fluorescence-boronic acid based system to measure the sucralose derivative in a multi-well plate. The architecture of the quenched fluorescence system utilizes a boronic acid receptor molecule to detect cis diols present on the sucralose derivative.


Others

Tech ID/UC Case

27127/2014-918-0


Related Cases

2014-918-0


Country/Region

USA

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