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A Novel High-Efficiency Algorithm for Optimizing Volumetric Modulated Arc Therapy (VMAT) Radiotherapy Treatment Planning

Technology Benefits

Much faster optimization (only 5-10 minutes on CPU and 25-30 seconds on GPU) compared to the hours required for existing algorithms. Reduces radiation dosage to the organs at risk (OARs) by computing a more conformed treatment volume for the target (compared to IMRT treatment plans).

Detailed Technology Description

UC San Diego researchers have developed an advanced aperture-based algorithm that significantly reduces the processing time for VMAT treatment plan optimization, permitting widespread clinical use of VMAT treatment techniques. This invention uses a column generation method that iteratively solves a sub-problem and a master problem efficiently. The sub-problem provides the most promising aperture to add to a given pool of allowable apertures while the master problem optimizes the intensities of selected apertures.

Supplementary Information

Patent Number: US20130131428A1
Application Number: US13695015A
Inventor: Jiang, Steve B. | Men, Chunhua | Jia, Xun
Priority Date: 28 Apr 2010
Priority Number: US20130131428A1
Application Date: 7 Jan 2013
Publication Date: 23 May 2013
IPC Current: A61N000510
US Class: 600001
Assignee Applicant: The Regents of the University of California
Title: OPTIMIZATION PROCESS FOR VOLUMETRIC MODULATED ARC THERAPY
Usefulness: OPTIMIZATION PROCESS FOR VOLUMETRIC MODULATED ARC THERAPY
Summary: Method for implementing volumetric modulated arc therapy (VMAT) for cancer treatment, for use in aperture-based radiation treatment system (claimed).
Novelty: Method for implementing volumetric modulated arc therapy (VMAT) for cancer treatment, of aperture-based radiation treatment system, involves using determined beam intensities of generated apertures to control radiation dose generation

Industry

Disease Diagnostic/Treatment

Sub Group

Cancer/Tumor

Application No.

9067064

Others

State Of Development

The planning efficiency and treatment plan quality of this novel VMAT optimization technology have been evaluated using ten clinical prostate or head-and-neck cases.

Tech ID/UC Case

20878/2010-287-0

Related Cases

2010-287-0, 2009-313-1, 2009-313-2, 2010-047-1, 2010-220-1

Country/Region

USA

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