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On-Demand Remote Control of Nanomotor Movement

Detailed Technology Description

UC San Diego researchers have developed methods for controlling the motion of artificial nanomotors. The invention pertains to on-demand remote control of the motion of catalytic, fuel-driven nanomotors in connection with external stimuli. For example, placing a microelectrode near the nanomotors and applying an electrochemical or thermal pulse turns the nanomotor on or off repeatedly. Further, on-demand control of nanomotor speed is achieved by controlling the temperature or potential during the thermal or electrochemical pulse, respectively. A network of microelectrodes can be used to control the speed and direction of the nanomotors along their path. In another example, the motion of bimetal nanowire motors (e.g., Au-Pt) is controlled by the presence of specific ions (e.g., trace Ag(I)) through a chemical-sensing mechanism. The invention is broad and can be applied to different types of nanomotors and different motion patterns.

Supplementary Information

Patent Number: US20130084569A1
Application Number: US13637645A
Inventor: Wang, Joseph | Wu, Jie | Balasubramanian, Shankar | Kagan, Daniel | Manesh, Kalayil Manian
Priority Date: 26 Mar 2010
Priority Number: US20130084569A1
Application Date: 11 Dec 2012
Publication Date: 4 Apr 2013
IPC Current: C12Q000168 | C07K001714 | C12N0015115 | G01N0033558 | G01N003358
US Class: 43500611 | 43500613 | 4350079 | 435188 | 436501 | 5303913 | 53602431 | 977726 | 977773 | 977920
Title: NANOMOTORS AND MOTION-BASED DETECTION OF BIOMOLECULAR INTERACTIONS
Usefulness: NANOMOTORS AND MOTION-BASED DETECTION OF BIOMOLECULAR INTERACTIONS
Summary: The method is useful for detecting biomolecular interactions used for detecting biological targets, preferably cancer biomarkers.
Novelty: Detecting biomolecular interactions useful for detecting biological targets e.g. cancer biomarkers, involves functionalizing nanomachine with capture probe, and detecting presence of biological targets