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NOVEL COMPOUNDS THAT BIND SELECTIVITY TO THE OPIOID RECEPTOR FOR THERAPEUTIC APPLICATIONS

Detailed Technology Description

None

Supplementary Information

Patent Number: US7776898B2
Application Number: US2007857193A
Inventor: Welsh, William J. | Yu, Seong Jae | Nair, Anil
Priority Date: 7 Feb 2002
Priority Number: US7776898B2
Application Date: 18 Sep 2007
Publication Date: 17 Aug 2010
IPC Current: A61K00314196 | A61P000102 | A61P000104 | A61P000304 | A61P000310 | A61P000706 | A61P000910 | A61P001102 | A61P001106 | A61P001108 | A61P001500 | A61P001702 | A61P001704 | A61P001706 | A61P001902 | A61P001906 | A61P002104 | A61P002500 | A61P002504 | A61P002506 | A61P002518 | A61P002522 | A61P002524 | A61P002528 | A61P002702 | A61P002900 | A61P003500 | A61P003702 | A61P004300 | C07D024908 | C07D024910 | C07D024914
US Class: 514383 | 5482622 | 5482648
Assignee Applicant: The Curators of the University of Missourilumbia
Title: Opioid receptor active compounds
Usefulness: Opioid receptor active compounds
Summary: (I) is used for the manufacture of a medicament useful for the treatment of pain (claimed), anxiety, obesity, depression, stress related disease, inflammation (e.g. in a disease like vascular disease, migraine headaches, periarteritis etc), headache, fever, arthritis (including rheumatoid arthritis, spondyloarthopathies, gouty arthritis, osteoarthritis, systemic lupus erythematosus and juvenile arthritis), asthma, bronchitis, menstrual cramps, tendonitis, bursitis, skin related conditions (e.g. psoriasis, eczema, burns and dermatitis), gastrointestinal conditions (e.g. inflammatory bowel disease, Crohn's disease, gastritis, irritable bowel syndrome and ulcerative colitis), cancer (e.g. colorectal cancer), ophthalmic disease (e.g. retinitis, retinopathies, conjunctivitis, uvetitis, ocular photophobia and acute injury to the eye tissue), pulmonary inflammation (such as that associated with viral infections and cystic fibrosis), central nervous system disorders (such as cortical dementias including Alzheimer's disease) and central nervous system damage (e.g. resulting from stroke, ischemia or trauma); for modifying the effects of other biologically active compounds (e.g. for treating narcotic addiction); for combating viral infections.
Novelty: New 4-(3-hydroxyphenyl) or 4-(3-alkoxyphenyl)-1,2,4-triazole compounds useful for treating e.g. pain, anxiety, obesity, depression

Industry

Disease Diagnostic/Treatment

Sub Group

Cancer/Tumor

Others

Country/Region

USA

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