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A novel approach to engineer proteins with improved stability

Summary

Researchers at Oklahoma State University have uncovered a novelmethod to engineer more stable protein variants. Based on a new set ofprinciples, this method is superior compared to previous methods, allowingresearchers to obtain very stable protein variants with ease. OSU researchershave already used this novel set of principles as a guide to introducemutations into a protein, which successfully engineered a protein variant withsubstantially improved stability.

Technology Benefits

· Novel method to generate stabileprotein variants · More efficient and robustthan previous methods· Standard, established proceduresto implement method

Technology Application

· Generatingproteins and enzymes resistant to heat, acid and alkaline conditions· Production ofenzymes for synthesis of amino acids · Generatingproteases for food processing, bioremediation and detergents· Bioconversionof starch, cellulose, chitin, pulp, proteins and fats. · Production ofbiofuels

Detailed Technology Description

None

Country/Region

USA

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