Air-assisted accelerator for low-pressure liquid chromatography (AAA-LPLC)

OSU researchers have created a compact air-assistedaccelerator device that converts common laboratory air valve supply into aclean and regulated pressure source.  Addinga pressure source to low-pressure liquid chromatography columns speeds upsolvent flow, resulting in equally pure samples within a much shorter timeframe,thereby increasing production speed.  Thisversatile device can be used for protein purification using affinity, ionexchange, desalting, and other chromatography methods.

Visualmonitoring of progressGreaterflexibility in terms of column size than spin column methodIncreasedsolvent flow rate in liquid chromatography columnsCompatiblewith affinity, ion exchange, and desalting chromatography methodsEffectivewith disposable gravity flow columns

DrugdevelopmentProteinseparationIdentificationof impuritiesDrugscreeningReplicationof natural products

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USA