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LocKiT Peptide Inhibitor of Nox1 NADPH Oxidase
Detailed Technology Description
Technology Description:Researchers have invented a short peptide that interferes with the phosphorylation of Nox1 and prevents its association with other co-factor proteins that are needed for its activation. The net effect is that this peptide “turns off” Nox1, resulting in decreased ROS production and abrogation of ensuing pathogenic phenotypes. Therefore, this peptide has potential to be used as a novel drug to block Nox1 activity in a variety of disease settings.
Country/Region
USA
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