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Increasing degradation of Hypoxia-Inducible Factors impairs cancer stem cell proliferation


Summary

This technology describes a method for treating ID2 protein-related diseases through increased degradation of Hypoxia-Inducible Factors (HIFs).


Technology Benefits

Mechanism-backed treatment of ID2 protein-related diseasesApplicable to multiple types of hypoxia-related cancersProvides multiple drug targets for increasing degradation of HIFs, reducing risk of resistance


Technology Application

Treatment and prevention of glioblastoma and other cancersTreatment and prevention of other ID2 protein-related diseasesResearch tool for developing additional targeted therapeutics


Detailed Technology Description

None


Country/Region

USA

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