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3D optical imaging with rapid, volume-based data acquisition at high spatiotemporal resolution

Summary

This technology is a 3D optical imaging system that enables simultaneous interrogation and monitoring of multiple local targets within a sample volume at high spatiotemporal resolution.

Technology Benefits

Provides high temporal resolution without compromising spatial resolutionEnables 3D imaging without mechanical motion, eliminating vibration error Capable of simultaneous photo-interrogation and monitoring of many targets within the sample volumeReduces photo-exposure via use of targeted illumination patternsCompatible with existing microscopes or as a stand-alone product

Technology Application

Three-dimensional microscopyHigh-frame-rate optical coherence tomographyFunctional imaging of neuronal activityMonitoring fluorescent signals indicative of cell-cell interactionsPotential monitoring of therapies that change the optical properties of tissuePhoto-stimulation of neuronal circuits using task-specific illumination patternsQuantification of neuronal activity in a 3D sample

Detailed Technology Description

None

Country/Region

USA

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