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Transgenic mouse strain allows inducible genetic expression in kidney cells and nervous system


Summary

Frank Costantini, Ph.D.


Technology Benefits

Provides ability to induce genetic modification in the kidney or nervous system at any time in the mouse developmentTransgenic mice develop normally without disorders associated with disruptions in the endogenous geneProvides cellular modification in parts of the nervous system that previous mice lines may not allowPatent information:Patent PendingTech Ventures Reference: IR CU14313


Technology Application

Strain of transgenic mice to conduct experiments involving inducible cellular modifications in kidney cells and/or the nervous systemPotential enhancement of GDNF in the endogenous GDNF-producing cells for therapeutic research for Parkinson's diseaseFurther research into how low nephron numbers affect hypertension


Detailed Technology Description

Frank Costantini, Ph.D.


Country/Region

USA

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