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Focused ultrasound planning system enables blood-brain barrier opening with a single element transducer

Summary

Elisa E. Konofagou, Ph.D.

Technology Benefits

Minimally invasive due to transient creation of small BBB opening.Safe and quick relative to techniques such as cranial surgery.Non-toxic compared to drug-based methods for BBB disruption.Highly localized and cost-effective for access to specific regions of the brain.Enables single element transducer, MR guidance-free procedures.Patent information:Patent Pending (WO/2011/079177)Tech Ventures Reference: IR 2687

Technology Application

Recurrent drug delivery in Alzheimer’s, Parkinson’s and other central nervous system diseases.Localized delivery of toxic drugs to a tissue site of interest.Research tool for finely controlled membrane manipulation. High throughput drug screening in vivo.

Detailed Technology Description

Elisa E. Konofagou, Ph.D.

Country/Region

USA

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