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Selective HDAC6 Inhibitor for the treatment of Alzheimer's and related diseases
Summary
Ronald Breslow, Ph.D.
Technology Benefits
Compounds target HDAC6 with 100-fold selectivity over HDAC1.Specific and selective inhibition of HDAC6 offers a therapy for the treatment of Alzheimer's and other neurological diseases while potentially minimizing off-target toxicities caused by pan-HDAC inhibitors. Patent information:Patent Pending (WO/2011/46855)Tech Ventures Reference: IR M10-078
Technology Application
Treatment of Alzheimer's disease through specific HDAC6 inhibition.Potentially useful for other central nervous system diseases such as Parkinson's and Huntington's.
Detailed Technology Description
Ronald Breslow, Ph.D.
Country/Region
USA
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