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Thiol-based surface chemistry allows for single molecule florescence studies of biomolecules
Technology Benefits
• Increased sensitivity in fluorescence microscopy studies.• Efficient single-molecule observations.• Greater accuracy in determining excitation events.• Eliminates necessity for performing background calibration experiments.Patent information: US 61/554,305 A1
Technology Application
• Single Molecule DNA sequencing• Bio-sensors• Protein studies • Enzyme-activity essays could be replaced or improved (ELISA)• Investigations of cellular metabolism• Nanoelectronics
Detailed Technology Description
Tech Ventures Reference: IR CU12055 Gold-based zero-mode waveguides are functionalized using thiol surface chemistry, enabling biocompatibility for single molecule fluorescence applications.Single molecule studies ...
Country/Region
USA
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