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Nkx3.1/Pten Mutant Mice for the Study of Prostate Carcinogenesis
Technology Benefits
These mice provide a model system for the study of the early stages of human prostate carcinogenesis
Technology Application
The study of prostate carcinogenesisCharacterization of the early stages of carcinogenesisDevelopment of potential treatments for prostate cancer
Detailed Technology Description
The Nkx3.1 homeobox gene has restricted expression in the prostate and essential role in prostate differentiation and function. PTEN represents a frequent target of mutational inactivation in human cancers, and Pten heterozygous mutant mice develop c...
Country/Region
USA
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