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Protein Therapy for Acute Lung Injury


Technology Benefits

Direct treatment of ARDSCan utilize a number of commercially-available transport proteins such as Chariot, perpetratin, and thrombin-antithrombin (TAT) fragmentFAKp may be fused to a histidine tag which can be linked to a variety of metals including copper, nickel, and zincMay be administered through an intravenous, buccal, parenteral, or oral route, or via inhalation


Technology Application

Treatment of


Detailed Technology Description

ARDS is characterized by the hyperpermeability of air sacs to fluid. This technology consists of a protein, focal adhesion kinase (FAKp), which prevents the endothelial cells of the lungs from becoming hyperpermeable. When delivered intravenously by ...


Country/Region

USA

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