CMOS optical sensor microarray for biomolecular detection

Ken Shepard, Ph.D.

Much less expensive, smaller, and more portable than typical fluorescence based detectors.Captures fluorescence lifetime data, providing additional information regarding the analyte's environment.On-chip design eliminates losses associated with complex optical setups normally required for fluorescence detection; increases sensitivity.Multi-fluorophore detection without the need for multiple optical filters.Additional background rejection and eases requirements on optical filters.Utilizes CMOS biosensor chip that enables time-gated, time-solved fluorescence spectroscopy.Enables high frame rate FLIM imaging. Patent Information:Patent Published (US7738086)Tech Ventures Reference: IR M05-070

Self-contained DNA and protein microarrays for gene sequencing and protein detection.General fluorescent lifetime sensor for use with confocal microscopy system. Active microarrays and high frame rate imagers for fluorescence lifetime imaging microscopy.

Ken Shepard, Ph.D.

USA