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Anti-properdin monoclonal antibody 3A3E1

Detailed Technology Description

Project #: D2016-44a Antigen Specificity: Human properdin purified from human plasma Clone: 3A3E1 Specificity: human properdin Host species: Mouse Reactive species: Rabbit properdin (no cross reaction with mouse or rat properdin) as determined by AP-mediated lysis of erythrocytes using serum from the mentioned species in the presence or absence of the monoclonal antibody. Description: Monoclonal antibody that inhibits properdin function by inhibiting its ability to bind to C3b. Applications: ELISA, Western Blot, AP50 Hemolysis Assay, Flow Cytometry References: Blatt AZ, Saggu G, Kulkarni KV, Cortes C, Thurman JM, Ricklin D, Lambris JD, Valenzuela JG, Ferreira VP. Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood. J. Immunol. (2016) 196: 4671-5680.

Country/Region

USA

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