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Nanobody L10 Method
Detailed Technology Description
There exists a critical, unmet need to molecularly profile defined cell-types throughout the mammalian brain. A neuron can be defined in multiple ways. For example, principal genetic markers, activity, and connectivity can be used to identify a cell type. With the advent of GENSAT, GFP reporter lines exist for a broad array of genetically-defined cell types throughout the brain, but there is no way to comprehensively profile these neurons. The current work describes a methodology for capturing the molecular profile of any cell type expressing GFP.
Country/Region
USA
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