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Waterproof Protein-Based Adhesives


Summary

Researchers at Purdue University are developing an effective surgical adhesive that shows promise in other applications as well. The glue uses a family of recombinantly produced proteins and an enzymatically modified amino acid to form a strong elastic bond between the soft tissues being joined. The structural control afforded by this genetic engineering approach will allow molecular level alterations to the material's properties for promise in future uses. For example, the challenging process of integrating biologically inert prostheses with native tissue could be improved by adhering growth factor domains on prostheses to promote cell proliferation. This novel material may also be used to prevent migration of cells after chondrocyte implantation in cartilage repair.


Technology Benefits

Matches soft tissue elasticity Genetic approach allows many possible future uses


Technology Application

Medical/Health Surgical adhesive to replace stitches and staples Prostheses Cartilage repair


Detailed Technology Description

Julie LiuPurdue Chemical Engineering


Countries

United States


Application No.

None


Country/Region

USA

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