Discontinuous Atmospheric Pressure Interface
Purdue University Researchers have developed discontinuous atmospheric pressure ionization (DAPI), which is a method of interfacing atmospheric pressure ion sources, including electrospray and desorption electrospray ionization sources, to mass spectrometers, for example miniature mass spectrometers, in which the ionized sample is discontinuously introduced into the mass spectrometer. Discontinuous introduction improves the match between the pumping capacity of the instrument and the volume of atmospheric pressure gas that contains the ionized sample. The reduced duty cycle of sample introduction is offset by operation of the mass spectrometer under higher performance conditions and by ion accumulation at atmospheric pressure.
Allows for smaller mass spectrometers Increases portability and field use
Mass spectrometers Field use of mass spectrometers
R. Graham CooksPurdue Biomedical EngineeringAston Labs
United States
9,058,967
USA
