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Biofunctional Membrane for Detection of Pharmaceuticals and Toxins

Summary

Researchers at Purdue University have developed novel approaches that allow the active transport structures on the biofunctional membranes to be oriented in large arrays and supported to provide directional transport and mechanical stability. This has been achieved using synthetic chemical and biological materials that are known to enhance stability. This approach will facilitate identification of promising pharmaceutical compounds, fingerprinting unknown environmental toxins based on membrane protein activity patterns, and rapid, high-throughput analysis of drug candidates for human multidrug resistance transporters and other membrane protein targets of disease.

Technology Benefits

AutomatedUses smaller quantities FasterStructure arrangement provides membrane with mechanical stabilityFacilitates identification of pharmaceutical compounds

Technology Application

Medical/HealthcarePharmaceuticalsDrug DeliveryBiotechnology

Detailed Technology Description

David ThompsonThompson GroupPurdue ChemistryPurdue Biomedical Engineering

Countries

United States

Application No.

7,374,944

Country/Region

USA

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