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Efficient Synthesis of HIV-1 Protease Inhibitors
Summary
Researchers at Purdue University have developed a new series of hexahydrofuropyran-derived HIV-1 protease inhibitors for treatment of HIV infection and AIDS. These inhibitors are novel and remarkably potent, similar to Darunavir, an FDA approved inhibitor also developed at Purdue. They also show excellent activity against multiple PI-resistant variants, superior to other FDA approved inhibitors.
Technology Benefits
High antiviral potencyEffective against wide range of variants
Technology Application
Medical/HealthcarePharmaceuticalsHIV/AIDS TreatmentDrug Development
Detailed Technology Description
Arun GhoshGhosh GroupPurdue Chemistry
Countries
United States
Application No.
9,024,038
Country/Region
USA
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