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A Class of Novel and Nonpeptide HIV-1 Protease Inhibitors

Summary

Purdue University researchers have designed and synthesized a novel class of HIV-1 protease inhibitors containing isophthalamide derivatives for the treatment of multidrug-resistant strains of HIV. These potent nonpeptide inhibitors are expected to possess improved pharmacological properties, are easy to synthesize in quantities, and will be further applicable for new drug development.

Technology Benefits

Novel HIV therapeutics with improved pharmacological propertiesEffective for the treatment of multidrug-resistant strains of HIV Simple chemical synthesis amenable to large-scale production

Technology Application

Medical/HealthcarePharmaceuticalsHIV/AIDS TreatmentDrug Development

Detailed Technology Description

Arun GhoshGhosh GroupPurdue Chemistry

Countries

United States

Application No.

9,085,571

Country/Region

USA

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