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Process and Intermediate Compounds for the Preparation of Pyrrolidines


Detailed Technology Description

Description of Technology Michigan State University’s invention relates to the preparation of pyrrolidines, preferably chiral, from tri-O-acetylketopentulosonic acid methyl esters. In particular, the invention relates to the preparation of 3,4-dihydroxy-5-hydroxymethyl pyrrolidines, which can be substituted or unsubstituted in the N position.  Patent Status U.S. patents 6,518,437; 6,482,973; 6,482,974; 6,492,543; and 6,583,297Japanese patent 3,394,047 Inventors Rawle Hollingsworth Tech ID TEC2000-0073


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USA

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