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Novel in vivo Metal Clusters with Activity Towards Misfolded Proteins
Detailed Technology Description
Auburn University is seeking a licensee or development partner for naturally occurring novel metal clusters that exhibit protein scavenging properties. Proteon nucleating centers (PNCs) consist of 1- to 2-nm nanoparticles that contain 40–300 non-ionic metal atoms. These nanoclusters have been shown to scavenge misfolded proteins to form proteons: clusters of up to 100,000 protein molecules with metal centers. Thus, PNCs have tremendous potential in the diagnosis and treatment of diseases associated with misfolded proteins, including prion-related diseases, neurological diseases, blood diseases and cancer.
Country/Region
USA

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