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Live Attenuated Vaccines for Francisella Noatunensis in Warm Water Fish


Detailed Technology Description

The live attenuated version of the pathogen, Francisella noatunensis subsp. orientalis, syn. F. asiatica, wascreated by mutations in the intracellular growth locus (igl). Tilapia gainedprotective immunity against wild-type Francisellaafter vaccination with the attenuated bacteria.


Countries

United States


Application No.

8,147,820


Country/Region

USA

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