AsiaIPEX is a one-stop-shop for players in the IP industry, facilitating IP trade and connection to the IP world. Whether you are a patent owner interested in selling your IP, or a manufacturer looking to buy technologies to upgrade your operation, you will find the portal a useful resource.
Novel Orally Available Treatment for Metabolic Syndrome & T2D
Technology Benefits
- Identified, designed and developed merged pharmacophore for sEH/PPAR dual modulators as a unique therapeutic approach- Novel dual modulators are orally available- Favorable absorption, distribution, metabolism and excretion properties- Avoid multidrug regimens and associated unpredictable drug-drug interactions- Modulation of PPAR╬│ regulates lipid metabolism, glucose homeostasis, anti-inflammatory processes- Modulating sEH/ has multiple cardio and kidney protective properties- Lead candidate decreases blood glucose and insulin resistance, improves heart function, prevents development of hypertension and end organ damage in spontaneously hypertensive obese rats (SHROB)
Detailed Technology Description
None
Country/Region
USA
For more information, please click Here
