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Chemo-Hydrothermal Method Increases Biocompatibility and More in Chitosan

Technology Benefits

Improved water solubility and dispersibility Increased biocompatibility

Technology Application

Antimicrobials Drug delivery Tissue engineering Bioimaging Biosensing Catalysis

Detailed Technology Description

This chemo-hydrothermal method is a one-step, one-pot synthesis. When the chitosan and a chemical cross-linker, such as tartaric acid, are cooked together under high pressure, its chemical properties remain unaltered. The chitosan-and-tartaric-acid composites form soluble nanoparticles that are also capable of solubilizing other insoluble materials, such as metal particles and metal oxide particles. When copper is added to this mixture, uniform-sized nanocomposites are formed and the pH level is raised to 7, making the composition neutral.

Country/Region

USA

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