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RhoB Variants for Suppression of Malignancy


Detailed Technology Description

Tumor types that might benefit from treatment by RhoB variants include lung, brain, pancreatic, prostate, and head and neck.Mutants of RhoB may retain tumor suppressive activity while being resistant to inactivation by other signaling proteins.RhoB variants may be combined with other interventions including radiation and chemotherapy.Delivery of RhoB may be as polypeptides or encoding nucleic acids.


Country/Region

USA

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