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1,1-DIOXO-1,2,6-THADIAZINE 2-SUBSTITUTED 5-CARBOXYLATE AND 5-CARBOXAMIDE DERIVATIVES WITH CANNABINOID PROPERTIES


Detailed Technology Description

None


Supplementary Information

Patent Number: WO2007054601A1
Application Number: WO2006ES70172A
Inventor: PAÉZ PROSPER, Juan Antonio | GOYA LAZA, María Pilar | CANO RAMOS, Carolina | MARTÍN FONTELLES, Maria Isabel | GIRÓN MORENO, Maria del Rocío | GOICOECHEA GARCÍA, Carlos
Priority Date: 11 Nov 2005
Priority Number: WO2007054601A1
Application Date: 8 Nov 2006
Publication Date: 18 May 2007
IPC Current: C07D028516 | A61K0031549
Assignee Applicant: Consejo Superior De Investigaciones Científicas | Universidad Rey Juan Carlos
Title: 1,1-DIOXO-1,2,6-THADIAZINE 2-SUBSTITUTED 5-CARBOXYLATE AND 5-CARBOXAMIDE DERIVATIVES WITH CANNABINOID PROPERTIES | DERIVADOS DE 5-CARBOXILATO Y 5-CARBOXAMIDA 2-SUSTITUIDOS DE 1,1-DIOXO-1,2,6-TIADIAZINA CON PROPIEDADES CANNABINOIDES | DERIVES DE 5-CARBOXYL
Usefulness: 1,1-DIOXO-1,2,6-THADIAZINE 2-SUBSTITUTED 5-CARBOXYLATE AND 5-CARBOXAMIDE DERIVATIVES WITH CANNABINOID PROPERTIES | DERIVADOS DE 5-CARBOXILATO Y 5-CARBOXAMIDA 2-SUSTITUIDOS DE 1,1-DIOXO-1,2,6-TIADIAZINA CON PROPIEDADES CANNABINOIDES | DERIVES DE 5-CARBOXYLATE ET 5-CARBOXAMIDE 2-SUBSTITUES DE 1,1-DIOXO-1,2,6-TIADIAZINE PRESENTANT DES PROPRIETES CANNABINOIDES
Summary: (I) Are useful as medicaments for treating disorders involving cannabinoid receptors, specifically for the treatment or prevention of glaucoma, bronchial asthma, chronic bronchitis, allergies (e.g. contact dermatitis or allergic conjunctivitis), arthritis, pain, organ transplantation problems, motor disorders associated with Tourette syndrome, Parkinson's disease, Huntington's chorea, malignant glioma, multiple sclerosis, emesis (and other toxic or undesirable side effects of anticancer chemotherapy), appetite disorders, acute schizophrenia or cognitive and memory disorders associated with Alzheimer's disease. (I) Are also useful for carrying out pharmacological tests for characterization of receptors and confirmation of agonist and antagonist activities (all claimed).
Novelty: New 1,1-dioxo-1,2,6-thiadiazine-5-carboxylic acid derivatives, useful as cannabinoid agonist/antagonist for treating e.g. glaucoma, asthma, allergies, arthritis, pain, emesis or schizophrenia


Industry

Disease Diagnostic/Treatment


Sub Group

Cancer/Tumor


Country/Region

USA

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