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Bacterial DNA fingerprint detection (Technion)

Summary

The invention is of a fast and highly accurate system for identifying the presence of bacteria, based on DNA sequence. The technology in capable of identifying bacterial strains, and assigns an identity number to bacterial strain based on a Simple Sequence Repeat (SSR). This technology can accurately, identify bacteria quite parallel to the human forensic database that the FBI builds up for criminal identification. The development of the bacterial DNA fingerprinting technology involves a unique combination of computer programming and molecular biology. The technology was originally designed to detect E. coli and distinguish between its different strains, was adapted to Listaeria and Cholera and can be easily adaptable to any other bacteria. This new technology can be developed into an automated system for process-line testing.
The product based on this new technology is a system for Automatic Detection and “Fingerprinting” of Bacterial Pathogens. It can be used to automatically detect the presence of bacteria in food, water, as well as in biological and medical samples. The precise identification of the bacterial strain can be of crucial importance in determining effective therapeutic strategies, epidemiology, detection of biological contaminants in water, consumer products, and biological samples.
The identification technology may be combined with any DNA detection technology. Such combinations were demonstrated to yield fast and accurate results as exemplified in the figure above.

Technology Application

USPTO Issued patent

ID No.

WAT-0526

Country/Region

Israel

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