Methods for determining the cause of somatic mutagenesis
The patent provides for a platform technology that implements the only known method able to use genetic sequence information to identify the source of many mutations in an individual to: 1. Identify the cause and nature of pre-cancerous conditions 2. Somatic hypermutation activity profiling for individuals before, during and following treatment and, 3.Track mutation changes for the worried well over their lifetime.
Global licensing/partnership opportunity - $1b+ market potential.
This invention is in the field of computational immunology and the application of genetic algorithms for methods to analyse nucleic acid sequence codes (DNA or RNA). More particularly, it provides a novel method for analysing genomic mutation patterns arising from somatic mutagenic processes associated with disease (e.g. cancer, AIDs and some neurodegenerative diseases). It involves the identification and characterisation of endogenous mutagenic agents and processes linked to the relatively elev
Sale, License agreement, Other (Business Parnter)
Inventor: LINDLEY, Robyn Alice
Priority Number: WO2014066955A1
IPC Current: C12Q000168
Title: METHODS FOR DETERMINING THE CAUSE OF SOMATIC MUTAGENESIS | PROCÉDÉS DE DÉTERMINATION DE LA CAUSE D'UNE MUTAGENÈSE SOMATIQUE
Usefulness: METHODS FOR DETERMINING THE CAUSE OF SOMATIC MUTAGENESIS | PROCÉDÉS DE DÉTERMINATION DE LA CAUSE D'UNE MUTAGENÈSE SOMATIQUE
Summary: For expression of recombinant proteins (claimed).
Novelty: New yeast host cell comprising 18S and/or international transcribed spacer ribosomal DNA sequence having specific accession number, useful for expression of recombinant proteins
Biomedical
DNA/Gene Engineering
patent application
To be identified by April 2015
Australia
