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Biomarkers of Gastric Cancer and Use Thereof

Summary

A set of biomarkers indicative of early gastric cancer and method of diagnosing gastric cancer at an early stage by directing the these biomarkers in a blood sample. Detection of over-expression of one or more protein biomarks in the group consisting albumin, T-kininogen I, [alpha]-2-HS glycoprotein, [alpha]-1-antitrypsin, afamin and [gamma]-actin and/or detection of under-expression of one or more protein biomarks in the group consisting stress 70 protein, apolipoprotein A-I, apolipoprotein A-IV, transthyretin and murinoglobulin is indicative of the presence of gastric cancer.

Supplementary Information

Patent Number: US8709732B2
Application Number: US13025183A
Inventor: Lo, Samuel Chun-Lap | Lam, Katie Wing Kei
Priority Date: 11 Feb 2010
Priority Number: US8709732B2
Application Date: 11 Feb 2011
Publication Date: 29 Apr 2014
IPC Current: G01N003353 | G01N0033574
US Class: 4350071 | 43500723
Assignee Applicant: The Hong Kong Polytechnic University
Title: Biomarkers of gastric cancer and use thereof
Usefulness: Biomarkers of gastric cancer and use thereof
Summary: The method is useful for assessing possibility of having gastric cancer in subject.
Novelty: Assessing possibility of having gastric cancer in subject, by detecting over-expression of protein biomarkers e.g. albumin, and afamin, and detecting under-expression of biomarkers e.g. stress-70 protein and transthyretin in sample

Industry

Disease Diagnostic/Treatment

Sub Group

Cancer/Tumor

Application No.

US13025183A

Others

LO Chun Lap Samuel
LAM Wing Kei Katie

Country/Region

USA

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