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The Usage of 1,3,5,7-tetrahydroxy-8-isoprenylxanthone, a Natural Compound from Garcinia Esculenta Y. H. Li, as Anti-inflammation Drugs


Summary

This invention relates to a chemical entity isolated from natural sources for its therapeutic uses.


Technology Benefits

Providing a natural compound from a natural source that exhibits potent anti-inflammatory effect


Technology Application

The compound can be developed as potential anti-inflammatory drugs


Detailed Technology Description

It relates to a compound 1,3,5,7-tetrahydroxy-8-isoprenylxanthone (TI), that is naturally occurring in the plant of Garcinia esculenta Y. H. Li, and its biological activity of inhibiting nitric oxide production and microRNA 155 expression in stimulated macrophages, which can be developed as potential anti-inflammatory drugs.


Supplementary Information

Inventor: LI, Lian-kui
Priority Number: CN101085163A
IPC Current: A61K0036896 | A61K003334 | A61K003555 | A61P003500
Title: Chinese medicinal herb for treating cancer | Chinese tradition medicinal herb for treating cancer
Usefulness: Chinese medicinal herb for treating cancer | Chinese tradition medicinal herb for treating cancer
Summary: For treating the cancer (e.g., lung cancer, liver cancer, gastric cancer, breast carcinoma, nose cancer, and esophagus cancer).
Novelty: Oral traditional Chinese medicinal herb for treating cancer (e.g. lung cancer) comprises Herba pellioniae radicantis, Herba catharanthi rosei, Scutellaria barbata, Chinese brake herb, Wahlenbergia marginate, Psychotria serpens


Industry

Disease Diagnostic/Treatment


Sub Group

Cancer/Tumor


Application Date

2013.01.11


Application No.

US 61/751,308


Others

Filed


ID No.

A61/BZ/Tetr/US0P


Country/Region

Hong Kong

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