用於對細胞進行損傷處理的機械損傷器
Mechanical cell wounder device and related method
This is a novel device and method for uniform cellular manipulation with economies of scale and operational uniformity. It introduces a multi-channel mechanical damaging device which is used for damaging cells and which comprises a pin support body, a plurality of pins, which are arranged in parallel and connected with the pin support body, and a handle which is connected with the pin support body; the length the pins extending out of the pin support body can be adjusted. The pin support body is provided with a plurality of holes; the pins can be inserted into the holes and are suitable for the one-time suction head which can be replaced. The multi-channel mechanical damaging device can also be provided with guide components, which are arranged on two sides of the pin support body; and the angle between the guide components can be regulated. In particular, the invention provides an 8-channel mechanical damaging device which can be used in the cell injury experiment of cells which are cultured by 96-hole microplate. It also provides a method which uses the multi-channel mechanical damaging device to damage the cell culture and an application thereof in cell migration and the potential biological phenomena thereof.
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Patent Number: CN101339104B
Application Number: CN200710127846A
Inventor: HUANG, Yue-shun | LIANG, Pei-xian | MAI, Nai-qi | YU, Ying-jie
Priority Date: 3 Jul 2007
Priority Number: CN101339104B
Application Date: 3 Jul 2007
Publication Date: 8 Jan 2014
IPC Current: G01N000128 | C12Q000100 | G01N003348
Assignee Applicant: Hong Kong Baptist University
Title: Mechanical damaging device for cell damage processing
Usefulness: Mechanical damaging device for cell damage processing
Summary: Device for damaging cells, during study on cell migration and potential biological phenomenon (all claimed).
Novelty: Device for damaging cells, has several pins having adjustable lengths connected with pin support to which handle is connected
2007.07.03
200710127846
Filed
G01/YY/Mech/CN01
Hong Kong
