Telomerase Reverse Transcriptase Fragments And Uses Thereof
The Invention Provides Compositions Comprising Fragments Of Human Telomerase Reverse Transcriptase (Htert) Which Can Lead To Telomere Dysfunction In A Cell And Reduction Of Growth And Tumorigenicity In Cancer Cells. The Invention Also Relates To Uses Of The Fragments In The Treatment Of Cancer And In Drug Discovery.
Patent Number: US7294708B2
Application Number: US2003449565A
Inventor: Huang, Jun Jian | Huang, Cui Fen | Lin, Marie C. M. | Kung, Hsiang Fu
Priority Date: 31 May 2002
Priority Number: US7294708B2
Application Date: 30 May 2003
Publication Date: 13 Nov 2007
IPC Current: C07H002102 | C12N000500 | C12N000912 | C12P002106 | A61K003800
US Class: 5360231 | 4350691 | 435325
Assignee Applicant: Beijing Institute of Biotechnology,Beijing | The University of Hong Kong
Title: Telomerase reverse transcriptase fragments and uses thereof
Usefulness: Telomerase reverse transcriptase fragments and uses thereof
Summary: The polypeptide is useful in preparing a composition for treating or preventing proliferative disease, e.g., cancer (claimed).
Novelty: New human telomerase reverse transcriptase polypeptide, useful in preparing a composition for treating or preventing proliferative disease, e.g., cancer
Disease Diagnostic/Treatment
Cancer/Tumor
Hong Kong