Anti- Aspergillus fumigatus cell wall proteins, IgM monoclonal antibody panel (15 lines)
- 詳細技術說明
- Applications Aspergillusfumigatusis a widespread saprobe that breaks down organic material in soil. The conidiaof this fungus are ubiquitous in the atmosphere and commonly inhaled. Inhealthy individuals, A. fumigatus cancause allergic reactions or localized infections. In the immunocompromised,however, it can cause invasive aspergillosis, an increasingly frequent andoften fatal disease. These monoclonal antibodies have been tested to ELISA and AF.
- *Abstract
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ReagentsDescription
Clone Name
Epitope (protein locus/region)
Validated Applications (Dilution)
12A6
Apical, no septa
ELISA (1:100), IF (1:100)
14B5
Conidium, basal, septa
ELISA, IF (neat)
16C4
Apical protein ~70kDa, no septa
ELISA (1:10), IF (1:10), IEM (1:10), WB (neat)
18A3
Apical, basal, no septa
ELISA (1:10), IF (1:10)
19H1
Narrow basal zone, septa
ELISA , IF (neat)
1C4
Apical, no septa
ELISA (1:10), IF (1:10)
1D2
Basal
ELISA, IF (neat)
1E2
Apical, no septa
ELISA , IF (1:10)
4G5
Narrow basal zone
ELISA , IF (neat)
5D4
Apical, no septa
ELISA , IF (1:10)
5H9
Conidium and basal, no septa
ELISA , IF (1:10)
8A1
Conidium and basal, no septa
ELISA , IF (1:10)
8C12
Narrow basal zone
ELISA , IF (neat)
8C8
Apical, no septa
ELISA (1:10), IF (1:10)
9F1
Apical, no septa
ELISA (1:10), IF (1:10)
Antigen:Cell wall proteins
Immunogen: A. fumigatus 237 isolated cell walls
Species Immunized: Mouse
Purification Method: used as supernatant
Antibody storage temperature: -80oC
References
Momany M,Lindsey R, Hill TW, Richardson EA, Momany C, Pedreira M, Guest GM, Fisher JF,Hessler RB, Roberts KA. The Aspergillus fumigatus cell wall is organized indomains that are remodelled during polarity establishment. Microbiology.2004 Oct;150(Pt 10):3261-8.
Ste-Marie L,Sénéchal S, Boushira M, Garzon S, Strykowski H, Pedneault L, de Repentigny L.Production and characterization of monoclonal antibodies to cell wall antigensof Aspergillus fumigatus. Infect Immun.1990 Jul;58(7):2105-14.
- 國家/地區
- 美國
