AsiaIPEX is a one-stop-shop for players in the IP industry, facilitating IP trade and connection to the IP world. Whether you are a patent owner interested in selling your IP, or a manufacturer looking to buy technologies to upgrade your operation, you will find the portal a useful resource.

Back to search results

Anti- Aspergillus fumigatus cell wall proteins, IgM monoclonal antibody panel (15 lines)

Detailed Technology Description: Applications Aspergillusfumigatusis a widespread saprobe that breaks down organic material in soil. The conidiaof this fungus are ubiquitous in the atmosphere and commonly inhaled. Inhealthy individuals, A. fumigatus cancause allergic reactions or localized infections. In the immunocompromised,however, it can cause invasive aspergillosis, an increasingly frequent andoften fatal disease. These monoclonal antibodies have been tested to ELISA and AF.

*Abstract

ReagentsDescription

Clone Name	Epitope (protein locus/region)	Validated Applications (Dilution)
12A6	Apical, no septa	ELISA (1:100), IF (1:100)
14B5	Conidium, basal, septa	ELISA, IF (neat)
16C4	Apical protein ~70kDa, no septa	ELISA (1:10), IF (1:10), IEM (1:10), WB (neat)
18A3	Apical, basal, no septa	ELISA (1:10), IF (1:10)
19H1	Narrow basal zone, septa	ELISA , IF (neat)
1C4	Apical, no septa	ELISA (1:10), IF (1:10)
1D2	Basal	ELISA, IF (neat)
1E2	Apical, no septa	ELISA , IF (1:10)
4G5	Narrow basal zone	ELISA , IF (neat)
5D4	Apical, no septa	ELISA , IF (1:10)
5H9	Conidium and basal, no septa	ELISA , IF (1:10)
8A1	Conidium and basal, no septa	ELISA , IF (1:10)
8C12	Narrow basal zone	ELISA , IF (neat)
8C8	Apical, no septa	ELISA (1:10), IF (1:10)
9F1	Apical, no septa	ELISA (1:10), IF (1:10)

Antigen:Cell wall proteins

Immunogen: A. fumigatus 237 isolated cell walls

Species Immunized: Mouse

Purification Method: used as supernatant

Antibody storage temperature: -80^oC

References

Momany M,Lindsey R, Hill TW, Richardson EA, Momany C, Pedreira M, Guest GM, Fisher JF,Hessler RB, Roberts KA. The Aspergillus fumigatus cell wall is organized indomains that are remodelled during polarity establishment. Microbiology.2004 Oct;150(Pt 10):3261-8.

Ste-Marie L,Sénéchal S, Boushira M, Garzon S, Strykowski H, Pedneault L, de Repentigny L.Production and characterization of monoclonal antibodies to cell wall antigensof Aspergillus fumigatus. Infect Immun.1990 Jul;58(7):2105-14.

Country/Region

USA

For more information, please click Here